#8 - Psilocybin: Pharmacology And Therapeutic Mechanisms

This episode explores the pharmacology (the science of drug action) and therapeutic mechanisms of Psilocybin as it relates to the brain and body.
Pharmacology is the science of drug action. Psilocybin, among other classical psychedelic compounds like LSD and mescaline, have common therapeutic mechanisms including functional connectivity (when more connections are established from the brain than in a normal waking state), neuroplasticity (the ability for the brain and nervous system to change), and modulation of the Default Mode Network (a brain network associated with self-concept).

This episode is a discussion of the pharmacology and therapeutic mechanisms of Psilocybin; the psychoactive component of the Psilocybe Mushrooms (aka "magic mushrooms"). Pharmacology is the use, effects, and modes of drug action. Where does psilocybin exert its effect in our body? How is it metabolized? What receptors in the brain and body does it attach to? What is the result of the change in physiology?

The scope of psychedelic research is expanding and it's only in the last couple of decades that we have been able to find how psilocybin, as well as other psychedelic compounds, exert their effect in the body.

This episode is part 1 of a two-part series exploring the pharmacology and therapeutic mechanisms of psilocybin and MDMA. 

Mind Medicine Australia 
Tommy Moore